Dr. Mtshali has made a name for herself as the youngest hospital CEO in South Africa at the age of 31. Her vast experience in both private and public healthcare have paved the way to where she is today. Her social consciousness can be attributed to her active role in student politics as a young SRC President at the University of KwaZulu-Natal, where she was the first female president of the medical school SRC. After completing her Bachelor of Medicine and Bachelor of Surgery at the University of KwaZulu-Natal, she went on to do her internship at the Helen Joseph Hospital and her community service at KwaMhlanga hospital in Mpumalanga. In 2010 she was headhunted to join Sakhiwo Health Solutions as a Marketing and Stakeholder Manager. After a year, she moved to Metropolitan Health Risk Management as a Medical Advisor. In 2012 she took on the role of the Clinical Manager at Far East Rand Hospital. During this process, she enrolled to study towards a Masters in Business Administration at the University of the Witwatersrand Business School. In 2015 she was requested by the HOD of Health in Gauteng to act in the position of CEO at the Bertha Gxowa Hospital. She does weekly walkabouts in various sections of the hospital to motivate and encourage staff and to get first-hand experience on all issues and challenges. Her appointment in March 2016 was welcomed by staff and represented the start of a new era of excellence for public healthcare services at Bertha Gxowa Hospital.